TCA may refer to:

Chemistry and biochemistry Toxin complex a, an insecticidal toxin complex produced by Photorhabdus luminescens bacteria Tricarboxylic acid cycle, an alternate name for the citric acid cycle pathway in cellular metabolism Trichloroacetic acid, chemical with many applications in biochemistry, cosmetic treatments, and medicine 2,4,6-Trichloroanisole, cause of cork taint in wine Tricyclic antidepressant, a class of medications TCA, a codon for the amino acid serine

Culture and media Taiwanese Cultural Association Tekeyan Armenian Cultural Association, a network of Armenian cultural organisations Television Critics Association The Canadian Amateur, radio amateur magazine Tribune Content Agency, a syndication company owned by Tribune Publishing Triple Crown of Acting is a term used in the American entertainment industry to describe actors who have won a competitive Academy Award, Emmy Award, and Tony Award in the acting categories Twentieth Century Animation, the animation division of 20th Century Studios

Economics and finance Transaction cost analysis Total cost of acquisition True cost accounting

Education The Classical Academy (Colorado), Colorado Springs, US Trinity Christian Academy (Deltona, Florida), US Trinity Christian Academy (Jackson, Tennessee), US

Organizations The Consulting Association, British organisation involved in blacklisting construction workers Total Community Action, New Orleans, USA; non-profit supporting disadvantaged residents Trans-Canada Air Lines, predecessor to Air Canada Train Collectors Association, for collectors/operators of toy trains Transportes Carga Aérea, a defunct Brazilian airline

Politics and government Taiwan Constitution Association, a political party in Taiwan EU–UK Trade and Cooperation Agreement, between the UK and the EU (2020) The Competition Authority (Ireland) (2002–2014)

Other uses Terminal control area, a volume of controlled airspace Topology change acknowledgement, a message in the 802.1D Spanning Tree Protocol (STP) Transportation Corridor Agencies, a toll road authority in Orange County, California Traumatic cardiac arrest, due to trauma Tennant Creek Airport, Northern Territory, Australia (IATA code: TCA) Turks and Caicos Islands, country code Tropical Cyclone Advisory, tropical forecast service for international aviation safety