Rusk is a dry biscuit. It may also refer to:

People Claude Ewing Rusk (1871-1931), author and mountaineer Dean Rusk (1909–1994), United States Secretary of State (1961–1969) Harry W. Rusk (1852–1926), American politician Jeremiah M. Rusk (1830–1893), American politician and U.S. Secretary of Agriculture (1889–1893) Lycurgus J. Rusk (1851-1928), American politician Rita Rusk (1947–2022), Scottish hairdresser Simon Rusk (born 1981), Scottish footballer Thomas Jefferson Rusk (1803–1857), Republic of Texas military officer and politician, U.S. Senator (1846–1857)

Places in the United States Rusk, Indiana, an unincorporated community Rusk, Texas, a city Rusk Independent School District Rusk, West Virginia, an unincorporated community Rusk, Burnett County, Wisconsin, a town Rusk, Dunn County, Wisconsin, an unincorporated community Rusk, Rusk County, Wisconsin, a town Rusk County, Texas Rusk County, Wisconsin Rusk Mountain, a peak in the Catskill Mountains, New York

Other uses Rusk Incorporated, a maker of hair care products and devices Rusk Institute of Rehabilitation Medicine, part of New York University Medical Center; named for Dr. Howard A. Rusk Dell Rusk, U.S. Secretary of Defense, an alias of Red Skull, a Marvel Comics villain

See also Rusk documents, diplomatic documents exchanged by the U.S. and Korea in the 1940s and 1950s Afroyim v. Rusk, a 1967 U.S. Supreme Court case