PWB may refer to:

Partial Weight-bearing, in which patients are instructed to put only a certain amount of weight on their leg after surgery Printed wiring board Psychological well-being Programmer's Workbench, an early UNIX from Bell Labs, see PWB/UNIX a Text-based user interface, Integrated development environment (IDE) by Microsoft, see History of Visual C++ Phoebe Waller-Bridge, English actress, playwright, producer, and writer.