Sob is a verb meaning cry. Sob and SoB may refer to:

Biomedicine Shortness of breath or dyspnea, a medical symptom relating to breathing difficulties Sobralia, a genus of orchids Super optimal broth, a bacterial growth medium

Music and media S.O.B. (film), a 1981 film by Blake Edwards The Sob, a 1953 Turkish film S.O.B. (band), a Japanese grindcore band "S.O.B." (song), by Nathaniel Rateliff and the Night Sweats, 2015 Scars on Broadway, an American rock band Sons of Batman, a group of characters in a Batman comics miniseries Sons of Butcher (band), a Canadian rock band Sons of Butcher (TV show), a cartoon inspired by the band Sounds of Blackness, an American vocal and instrumental ensemble SOB's, Sounds of Brazil, a live music venue in New York City Sobs (band), a Singaporean indie rock band Styles of Beyond, an underground rap group Switched-On Bach, an album by Walter Carlos S.O.B.s, an episode of the television series Arrested Development

Transport Seaford–Oyster Bay Expressway Balaton Airport, SOB in IATA code South Bend station (Amtrak), SOB is its station code Southbourne railway station, SOB in Network Rail code Stadt-Omnibus Bern, a former public transport operator in Bern, Switzerland Südostbahn, a railway company in Switzerland SüdostBayernBahn, a railway company in southern Germany MS Spirit of Britain, a Dover–Calais P&O Ferry

Toponyms Sob (river), a river in Siberia, a tributary of the Ob Sob River, a river in Ukraine, a tributary of Southern Bug S.O.B. Hill, a mountain in Utah, United States

Others Souls on Board (sometimes POB for People on Board), used in Aviation communication Seventeen or Bust, a distributed computing project Special Operations Battalion (SOB), an elite unit of the Croatian army Society of Old Brooklynites, a civic organization Son of a bitch, an insult or curse phrase, sometimes abbreviated as "S.O.B." Sons of Ben (MLS supporters association) Suggested opening bid, a term in auctioneering Super Oralloy Bomb, a nuclear bomb Senate Office Building Dirksen Senate Office Building Russell Senate Office Building Hart Senate Office Building Sulfur-oxidizing bacteria, participating to the sulfur cycle