E450 or E-450 may refer to:
E450 (food additive) E-450, a Ford E-Series van or minibus Olympus E-450, a camera ThinkPad E450, laptop E450, a model variant of the Mercedes-Benz E-Class (W213) E-450, an AMD processor with 3D graphics E450 series, a Sony Walkman digital audio player, see Walkman E Series
See also
Sun Enterprise 450, a Sun Enterprise server computer Canon EOS 450D, a camera 450 (disambiguation)