L5 or L-5 may refer to:
Entertainment L5 (band), French female pop music group L5 Games, video games developer published by Gravity Interactive Gibson L5, electric guitar "Home on Lagrange (The L5 Song)", a filk song
Science Haplogroup L5 (mtDNA), human mitochondrial DNA haplogroup L5, the fifth lumbar vertebra Lagrangian point 5 in an astronomical solar system Lp space for p=5 Ribosomal protein L5, a human gene Ubiquitin carboxyl-terminal hydrolase L5, a human gene
Transportation GPS L5, a GPS signal Stinson L-5 Sentinel, aircraft used by the United States Army Air Forces in World War II Barcelona Metro line 5 HMS L5, a 1917 British L class submarine Junkers L5, a 1920s German six-cylinder, water-cooled, inline aircraft engine PRR L5, an American electric locomotive SP&S Class L-5, an 1897 steam locomotives class Strv L-5, a 1929 Swedish tank designed by Landsverk USS L-5 (SS-44), a 1916 United States Navy L-class submarine L5, an S-Bahn line of the Léman Express in Switzerland
Other uses L5 Society, a society promoting Dr. Gerard K. O'Neill's vision of space colonization ISO/IEC 8859-9 (Latin-5), an 8-bit character encoding
See also 5L (disambiguation) Level 5 (disambiguation)