Sir William Samwell (1559–1628) of Northampton and Uptonsamwell1 - Stirnet. Retrieved 2018-02-28. was an Auditor of the Exchequer to Queen Elizabeth I of England. He was knighted at the coronation of King James I of England in 1603.Kimber, E. and Johnson, R. The Baronetage of England: Containing a genealogical and historical account of all the English Baronets, volume 2, page 248. London, 1771
His nephew was James Harrington (1611–1677), English political philosopher, best known for his controversial work, Oceana.
His grandson was William Samwell (1628–1676), English architect.
The Samwell baronets were created for his great-grandson Sir Thomas Samwell, 1st Baronet.
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