LSE may refer to:
Education London School of Economics, a public research university within the University of London Lahore School of Economics, a private university in Lahore, Punjab, Pakistan Lincoln Southeast High School, a public government education school located in Lincoln, Nebraska Louvain School of Engineering, faculty of engineering science at the University of Louvain (UCLouvain), Belgium
Computing ("Symbolic teaching language"), a computer programming language Language-Sensitive Editor, a text editor used on Digital Equipment Corporation's VMS operating system Large system extensions, a set of atomic memory operations such as fetch-and-add for the 64-bit ARM (AArch64) architecture Latent sector error, an unrecoverable read error on a hard disk drive which has not yet been discovered
Finance Lahore Stock Exchange, now Pakistan Stock Exchange London Stock Exchange London Stock Exchange Group, the owner group of the London Stock Exchange
Transport La Crosse Regional Airport, Wisconsin, United States (IATA code LSE) La Crosse station - Amtrak code LSE Luzern–Stans–Engelberg railway line, a mountain railway in Switzerland
Other uses Load serving entity, an electricity demand aggregator in the deregulated market. Landing ship, Emergency Repair, a US WW2 Navy ship Least-squares estimation, a statistical technique commonly used in data fitting Lengua de signos española, Spanish Sign Language Logical Sensory Extrovert, a socionics personality type Lysergic acid ethylamide, also known as LAE or LAE-32, an LSD-related psychedelic drug