Harpalyce or Harpalyke may refer to:

Harpalyce (mythology), several women in Greek mythology Harpalyce (plant), a genus in the family Fabaceae of flowering plants Harpalyce, a ship sunk by UB-4 during World War I Harpalyke (moon), a moon of Jupiter Delias harpalyce, an Australian butterfly in the family Pieridae Harpalyce, character in the Teseida by Boccaccio.