Manolito is a diminutive form of the Spanish given name Manolo, in turn a diminutive of Manuel. It may refer to:
People Ramón Antonio "Manolito" Ramírez (born 1974), Dominican politician and businessman Manolito "Lito" Tolentino Mayo (1954–1983), Filipino artist and professor
Fictional characters Manuel "Manolito" Goreiro, a character in the Mafalda universe by Argentine cartoonist Quino Manolito Gafotas, the main character in a series of children's books by Spanish author Elvira Lindo Manolito Four Eyes, a 1999 comedy film based on the character Manolito Montoya, a character on the US TV series The High Chaparral
Other uses Manolito y su Trabuco, a Cuban salsa band
See also Manolita Manolo