Berthelot (, ) may refer to:

People with the surname Amable Berthelot (1777–1847), Québécois lawyer and political figure André Berthelot (1862–1938), a secretary-general of La Grande Encyclopédie Anne Berthelot (born 1957), French professor of Medieval literature studies Armond J. Berthelot (1894–1961), French World War I flying ace Chantal Berthelot, member of the French National Assembly for French Guiana (2007–2017) Charles Honoré Berthelot La Villeheurnois (c. 1750-1799), French politician Francis Berthelot (born 1946), French science fiction author Henri Mathias Berthelot (1861–1931), French general during World War I Jean-Michel Berthelot (1945–2006), French sociologist and philosopher Jeanne Agnès Berthelot de Pléneuf, marquise de Prie (1698–1727) Marcellin Berthelot (1827–1907) chemist, author and diplomat Marco Berthelot (born 1972), Canadian curler Michel-Amable Berthelot Dartigny (1738–1815), Canadian politician Philippe Berthelot (1866–1934), French diplomat Pierre Berthelot (1943-2023), French mathematician René Berthelot (? – 1664), French actor from Molière's troupe, known as Du Parc and Gros René Sabin Berthelot (1794–1880), French naturalist and ethnologist Sophie Berthelot (1837–1907), wife of Marcellin and mother of André and Philippe, first woman interred in the Panthéon

Places Berthelot River (Mégiscane River), a tributary of the Mégiscane River in Quebec, Canada Berthelot Lake (Mégiscane River), Quebec, Canada Avenue Berthelot, an avenue in the city of Lyon, France

See also Berthelot's reagent in analytical chemistry, invented by Marcellin Berthelot General Berthelot, a Romanian commune named after Henri Mathias Berthelot, previously named Berthelot