Okereke is a surname of Nigerian origin. Notable people with the surname include:
Barbara Okereke (born 1990), Nigerian entrepreneur Bobby Okereke (born 1996), American gridiron football player Chioma Okereke, British-Nigerian author David Okereke (born 1997), Nigerian footballer Emeka Okereke (born 1980), Nigerian photographer and filmmaker Kele Okereke (born 1981), English musician Ndi Okereke-Onyiuke (born 1950), Nigerian financier and stockbroker Stephanie Okereke Linus (born 1982), Nigerian actress and director Tasha Okereke and Tracie Okereke (born 1995), Brazilian rapper duo