Higuaín is a Basque surname. Notable people with the surname include:
Jorge Higuaín, an Argentine central defender, father of Federico and Gonzalo Higuain Gonzalo Higuaín, former professional footballer who played as a striker, Jorge Higuain's son and Federico's younger brother Federico Higuaín, former professional footballer who played as a forward, Jorge Higuain's son and Gonzalo's older brother