Pyrophosphatases, also known as diphosphatases, are acid anhydride hydrolases that act upon diphosphate bonds.
Examples include: Inorganic pyrophosphatase, which acts upon the free pyrophosphate ion Tobacco acid pyrophosphatase, which catalyses the hydrolysis of a phosphoric ester Various organic pyrophosphatases, which act upon organic molecules with the pyrophosphate group (but excluding triphosphatases that act on the final bond): Thiamine pyrophosphatase
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