This page contains tables of azeotrope data for various binary and ternary mixtures of solvents. The data include the composition of a mixture by weight (in binary azeotropes, when only one fraction is given, it is the fraction of the second component), the boiling point (b.p.) of a component, the boiling point of a mixture, and the specific gravity of the mixture. Boiling points are reported at a pressure of 760 mm Hg unless otherwise stated. Where the mixture separates into layers, values are shown for upper (U) and lower (L) layers.
The data were obtained from Lange's 10th editionLange's Handbook of Chemistry, 10th ed. pp. 1496–1505 and CRC Handbook of Chemistry and Physics 44th editionCRC Handbook of Chemistry and Physics, 44th ed. pp. 2143–2184 unless otherwise noted (see color code table).
A list of 15825 binary and ternary mixtures was collated and published by the American Chemical Society. An azeotrope databank is also available online through the University of Edinburgh.
Binary azeotropes Data source color code CRC & Lange's CRC only Lange's only other (see references)
+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various alcohols ethanol 78.4 78.1 95.5 0.804 methanol 64.7 No azeotrope 1-propanol 97.3 87.7 71.7 0.866 2-propanol 82.5 80.4 87.7 0.818 n-butanol 117.8 92.4 55.5U 79.9L 7.7 U 0.849L 0.990 sec-butanol 99.5 88.5 67.9 0.863 isobutanol 108.0 90.0 70.0U 85.0L 8.7 U 0.839L 0.988 tert-butanol 82.8 79.9 88.3 allyl alcohol 97.0 88.2 72.9 0.905 furfuryl alcohol 169.4 98.5 20 cyclohexanol 161.1 97.8 20 benzyl alcohol 205.4 99.9 9 with various organic acids formic acid 100.8 107.3 77.5 acetic acid ‡ 118.1 No azeotrope propionic acid 141.1 99.98 17.7 1.016 butyric acid 163.5 99.94 18.4 1.007 isobutyric acid 154.5 99.3 21 with mineral acids nitric acid 83.0 120.5 68 1.405 perchloric acid 110.0 203 71.6 hydrofluoric acid 19.9 120 37 hydrochloric acid –84 110 20.24 1.102 hydrobromic acid –73 126 47.5 1.481 hydroiodic acid –34 127 57 sulfuric acid 290 338 98 with various alkyl halides ethylene chloride 83.7 72 91.8 propylene chloride 96.8 78 89.4 chloroformComposition of Vapors from Boiling Binary Solutions J. J. Conti, D. F. Othmer, Roger Gilmont. J. Chem. Eng. Data, 1960, 5 (3), pp. 301–307 61.2 56.1 97.2U 0.8L 99.8 U 1.004L 1.491 carbon tetrachloride 76.8 66.8 95.9U 0.03L 99.97 U 1.000L 1.597 methylene chloride 40.0 38.8 99.6U 2.099.9 U 1.009L 1.328 with various esters ethyl acetate 77.1 70.4 91.9U 96.7L 8.7 U 0.907L 0.999 methyl acetate 57.0 56.1 95.0 0.940 n-propyl acetate 101.6 82.4 86 isopropyl acetate88.775.988.9 ethyl nitrate 87.7 74.4 78 with various other solvents acetone ‡ 56.5 No azeotrope methyl ethyl ketone 79.6 73.5 89 0.834 pyridine 115.5 92.6 57 1.010 benzene 80.2 69.3 91.1U 99.94L 0.07 U 0.880L 0.999 toluene 110.8 84.1 79.8U 99.95L 0.06 U 0.868L 1.000 cyclohexane 80.7 69.8 91.5U 99.99L 0.01U 0.780L 1.00CPME1068383.7MTBE5552.996.5 diethyl ether 34.5 34.2 98.7 0.720 tetrahydrofuran 66 64.2 95 2-methyltetrahydrofuran80.27189.4 anisole 153.9 95.5 59.5 acetonitrile 82.0 76.5 83.7 0.818 chloral 97.75 95.0 93.0 hydrazineMerck Index of Chemicals and Drugs, 9th ed. monograph 4653 113.5 120.3 68.5 m-xylene 139.0 92.0 64.2 ‡ CRC 44th ed. lists azeotropes for acetic acid/water and acetone/water, Lange's 10th ed. as well as numerous web sources indicate no azeotrope for these pairs.
+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various solvents methyl butyrate 102.7 93.8 45 n-propyl acetate 101.6 94.2 47 benzene 80.2 76.8 82.6 0.874 toluene 110.8 92.4 50 cyclohexane 80.8 74 80 carbon tetrachloride 76.8 72.3 88.5 1.450 ethylene chloride 83.7 79.9 82 + 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various esters ethyl acetate 77.1 71.8 69.2 0.863 methyl acetate 57.0 56.9 97 ethyl nitrate 87.7 71.9 56 isopropyl acetate 88.4 76.8 47 with various hydrocarbons benzene 80.2 68.2 67.6 0.848 cyclohexane 80.7 64.9 69.5 toluene 110.8 76.7 32 0.815 n-pentane 36.2 34.3 95 n-hexane 68.9 58.7 79 0.687 n-heptane 98.5 70.9 51 0.729 n-octane 125.6 77.0 22 with various alkyl halides ethylene chloride 83.7 70.5 63 chloroform 61.1 59.4 93 1.403 carbon tetrachloride 76.8 65.1 84.2 1.377 allyl chloride 45.7 44 95 n-propyl chloride 46.7 45.0 93 isopropyl chloride 36.3 35.6 97.2 n-propyl bromide 71.0 62.8 79.5 isopropyl bromide 59.8 55.6 89.5 n-propyl iodide 102.4 75.4 56 isopropyl iodide 89.4 71.5 73 methyl iodide 42.6 41.2 96.8 methylene chloride 40.1 39.85 95.0 ethyl bromide 38.0 37.0 97.0 trichloroethylene 87 70.9 73.0 1.197 trichlorotrifluoroethane (CFC 113) 47.7 43.8 96.2 1.517 tetrachloroethylene 121.0 76.75 37.0 with various other solvents water 78.4 78.1 4.5 0.804 methyl ethyl ketone 79.6 74.8 60 0.802 acetonitrile 82.0 72.9 43.0 0.788 nitromethane 101.3 75.95 26.8 tetrahydrofuranP = 100 kPa 65.6 65 96.7 2-methyltetrahydrofuran80.274.466 thiophene 84.1 70.0 55.0 carbon disulfide 46.2 42.4 92
+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various esters methyl acetate 57.0 53.8 81.3 0.908 ethyl acetate 77.1 62.3 56 0.846 ethyl formate 54.1 51.0 84 with various hydrocarbons benzene 80.2 58.3 60.5 0.844 toluene 110.8 63.8 31 0.813 cyclohexane 80.8 45.2 62.8U 97.0L 39.0 n-pentane 36.2 30.8 91 n-hexane 68.9 60 71.6 n-heptane 98.5 59.1 48.5 n-octane 125.8 63.0 72.0 with various alkyl halides methylene chloride 40.0 37.8 92.7 ethylene chloride 83.7 61.0 68 chloroform 61.1 53.5 87.4 1.342 carbon tetrachloride 76.8 55.7 79.4 1.322 ethyl bromide 38.4 35.0 95.5 n-propyl chloride 46.6 40.5 90.5 isopropyl chloride 36.4 33.4 94 n-propyl bromide 71.0 54.5 79 isopropyl bromide 59.8 48.6 85.0 isopropyl iodide 89.4 61.0 62 trichloroethylene 87.2 60.2 64 tetrachloroethylene 121.1 63.5 40.6 trichlorotrifluoroethane (CFC 113) 47.7 39.9 94 with various other solvents nitromethane 101.2 64.6 9 acetone 56.5 55.7 87.9 0.796 acetonitrile 82.0 63.45 19.0 carbon disulfide 46.2 37.7 86.0U 50.8L 97.2 U 0.979L 1.261 isopropyl alcohol 82.5 64.0 20 tetrahydrofuranP = 984 mBar 65.6 60.7 69.0 2-methyltetrahydrofuran80.262.743MTBE5551.368.6+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various solvents methyl butyrate 102.7 94.4 51 n-propyl formate 80.8 80.65 97 n-propyl acetate 101.6 94.7 49 0.833 benzene 80.2 77.1 83.1 toluene 110.8 92.4 47.5 0.836 n-hexane 68.9 65.7 96 carbon tetrachloride 76.8 73.1 88.5 1.437 ethylene chloride 83.7 80.7 81 n-propyl bromide 71.0 69.7 91 2-methyltetrahydrofuran80.279.599
+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various solvents benzene 80.2 80.05 98 0.882 cyclohexane 80.8 79.7 98 toluene 110.8 105.0 72 0.905 m-xylene 139.0 115.4 27.5 0.908 mesitylene 164.6 118 3.6 n-heptane 98.5 92.3 70 n-octane 125.8 109.0 50 isopropyl iodide 89.2 88.3 91 carbon tetrachloride 76.8 76.6 97 tetrachloroethylene 121.0 107.4 61.5 ethylene bromide 131.7 114.4 45 1,1-dibromoethane 109.5 103.7 75.0 methylene bromide 98.2 94.8 84.0 pyridine 115.3 139.7 65.0 1.024+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various esters ethyl acetate 77.1 75.3 75 0.869 isopropyl acetate 91.0 81.3 40 0.822 with various hydrocarbons benzene 80.2 71.9 66.7 0.838 toluene ‡ 110.8 80.6 42 cyclohexane 80.7 68.6 67.0 0.777 n-pentane 36.2 35.5 94 n-hexane 68.9 62.7 77 n-heptane 98.5 76.3 46 with various alkyl halides carbon tetrachloride 76.8 69.0 82 1.344 chloroform 61.1 60.8 95.8 ethylene chloride 83.7 74.7 56.5 ethyl iodide 83.7 67.1 85 n-propyl chloride 46.7 46.4 97.2 n-propyl bromide 71.0 66.8 79.5 isopropyl bromide 59.8 57.8 88 n-propyl iodide 102.4 79.8 58 isopropyl iodide 89.4 76.0 68 tetrachloroethylene 121.1 81.7 19.0 with various other solvents methyl ethyl ketone 79.0 77.5 68 0.800 diisopropyl ether 69 66.2 85.9 nitromethane 101.0 79.3 70 2-methyltetrahydrofuran80.27782 ‡ CRC and Lange's disagree on this azeotrope, but web source corroborates CRC + 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various hydrocarbons benzene 80.2 71.7 69 toluene 110.8 85.8 50 m-xylene 139.0 94.2 29.8 m-xylene 139.0 92.8 28.2 o-xylene 143.6 95.5 26 p-xylene 138.4 ~95 30.0 n-pentane 36.2 34.2 90 n-hexane 68.9 60.6 72 n-heptane 98.5 78.2 56.5 n-octane 125.8 90.5 37 with various alkyl halides chloroform 61.2 59.2 85 carbon tetrachloride 76.8 66.7 81.5 methyl iodide 42.6 42.1 94 ethyl bromide 38.4 38.2 97 ethylene chloride 83.6 77.4 86 ethylene bromide 131.7 94.7 48.5 n-propyl chloride 46.7 45.6 92 isopropyl chloride 34.8 34.7 98.5 n-propyl bromide 71.0 64.7 73 isopropyl bromide 59.4 56.0 86 with various other solvents carbon disulfide 46.3 42.6 83
+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav cyclohexane 80.74 77.8 45.0 0.834 ethyl nitrate 88.7 80.03 12.0 methyl ethyl ketone 79.6 78.4 37.5 0.853 nitromethane 101.0 79.15 14.0 acetonitrile 82.0 73.0 34.0 n-heptane 98.5 80.0 1 + 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav with various solvents ethyl benzoate 212.6 186.1 53.5 diphenyl 254.9 192.0 36 mesitylene 164.6 156.0 87 naphthalene 218.1 183.9 49 toluene 110.8 110.2 93.5 m-xylene 139.0 135.6 85 o-xylene 144.4 139.6 84.0 ethylene bromide 131.7 129.8 96 nitrobenzene 210.9 185.9 41 chlorobenzene 132.0 130.1 5.6 benzyl chloride 179.3 167.0 70 benzyl alcohol 205.1 193.1 44 anisole 153.9 150.5 89.5 acetophenone 202.1 185.7 48 aniline 184.4 180.6 76 o-cresol 191.1 189.6 73
+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav diphenyl 254.9 243.8 45 naphthalene 218.1 215.2 90
+ 2nd Component b.p. ofcomp. (˚C) b.p. ofmixture (˚C) % byweight spef.grav carbon disulfide 46.3 39.3 67.0 1.04 chloroform 61.2 64.7 80.0 1.268 cyclohexane 80.74 53.0 33.0 n-hexane 68.8 49.8 41 ethyl iodide 56.5 55.0 40.0 carbon tetrachloride 76.8 56.2 11.9
+ component 1 b.p.comp. 1 (˚C) component 2 b.p.comp. 2 (˚C) b.p.azeo. (˚C) % wtcomp. 1 % wtcomp. 2 spec.grav. acetaldehyde 21.0 diethyl ether 34.6 20.5 76.0 24.0 0.762 n-butane –0.5 –7.0 16.0 84.0 acetamide 222.0 benzaldehyde 179.5 178.6 6.5 93.5 nitrobenzene 210.9 202.0 24.0 76.0 o-xylene 144.1 142.6 11.0 89.0 acetonitrile 82.0 ethyl acetate 77.15 74.8 23.0 77.0 toluene 110.6 81.1 76.0 24.0 acetylene –86.6 ethane –88.3 –94.5 40.7 59.3 aniline 184.4 o-cresol 191.5 191.3 8.0 92.0 carbon disulfide 46.2 diethyl ether 34.6 34.4 1.0 99.0 0.719 1,1-dichloroethane 57.2 46.0 94.0 6.0 methyl ethyl ketone 79.6 45.9 84.7 15.3 1.157 ethyl acetate 77.1 46.1 97 3 methyl acetate 57.0 40.2 73 27 chloroform 61.2 methyl ethyl ketone 79.6 79.9 17.0 83.0 0.877 n-hexane 68.7 60.0 72.0 28.0 1.101 carbon tetrachloride 76.8 methyl ethyl ketone 79.9 73.8 71.0 29.0 1.247 ethylene dichloride 84.0 75.3 78.0 22.0 1.500 ethyl acetate 77.1 74.8 57.0 43.0 1.202 cyclohexane 80.74 ethyl acetate 77.15 72.8 46.0 54.0 ethyl nitrate 88.7 74.5 64.0 36.0 diethyl ether 34.6 methyl formate 31.50 28.2 44.0 56.0 methylene chloride 40 40.8 30 70 nitromethane 101.0 toluene 110.8 96.5 55.0 45.0 tetrahydrofuran 65.6 chloroform 61.2 72.5 34.5 65.5 n-hexane 69 63.0 46.5 53.5 toluene 110.63 pyridine 115.3 110.2 78.0 22.0 2-methyltetrahydrofuran80.2none - - propylene glycol 188.2 aniline 184.4 179.5 43 57 o-xylene 144.4 135.8 10 90 toluene 110.6 110.5 1.5 98.5
Ternary azeotropes Tables of various ternary azeotropes (that is azeotropes consisting of three components). Fraction percentages are given by weight.
Data source color code CRC & Lange's CRC only Lange's only other (see references)