Twist of Fate may refer to:

Film and television Twist of Fate (1954 film), British-American mystery Twist of Fate, 1998 Canadian-American thriller, a/k/a Psychopath, with Mädchen Amick Twist of Fate (1989 TV series), British drama TV miniseries Twist of Fate (2011 TV series), American documentary Twist of Fate (2016 TV series), Indian English-language soap opera Twist of Fate, international name of 2014 Indian television series Kumkum Bhagya "Twist of Fate" (Atlantis), a 2013 television episode

Music "Twist of Fate" (Olivia Newton-John song), 1983 "Twist of Fate" (Emilia Rydberg song), 1998 "Twist of Fate" (Siobhán Donaghy song), 2003 A Twist of Fate, 2003 EP by John Arch Twist of Fate, a 2010 single by Bad Lieutenant also featured on the 2009 album Never Cry Another Tear

Other Twist of Fate, professional wrestling move variation of cutter, popularized by The Hardy Boyz, consisting of Jeff Hardy and Matt Hardy

See also A Simple Twist of Fate, 1994 American comedy-drama vehicle for Steve Martin Twist of Faith (disambiguation)