Holyoake is a surname. Notable people with the surname include:

Francis Holyoake (1567–1653), British lexicographer George Holyoake (1817–1906), English secularist and co-operator Henry Holyoake (1657–1731), headmaster of Rugby School Holly Holyoake (born 1988), Welsh classical music singer Sir Keith Jacka Holyoake (1904–1983), New Zealand politician Ronald Holyoake (1894–1966), English cricketer Thomas Holyoake (1616?–1675), Church of England cleric

Places Holyoake, Western Australia, a locality in Western Australia

See also Holyoak, surname Hollioake, surname Holyoke (disambiguation)