Kassab is a surname, a variant of Qasab. Other variants of the name are Cassab and Casap (especially in Latin America). Notable people with the surname include:

Alejandro Hagano Cassab aka Gran Sandy (1937–2005), Bolivian-Argentine comedian and entertainer Barbara Kassab-Every (1945−2013), Dutch artist Freddy Kassab, involved in the Fatal Vision controversy Jibrail Kassab (born 1938), bishop of the Chaldean Catholic Church in Australia Gilberto Kassab (born 1960), Brazilian politician, mayor of São Paulo May Kassab (born 1981), Egyptian singer Nimatullah Kassab (1808−1858), Lebanese monk, scholar and saint Théophile Georges Kassab (1945−2013), Syrian Syriac Catholic archbishop Yumna Kassab, Australian novelist

See also Kessab, or Kassab, a town in Syria Kasab (disambiguation) Qasab (disambiguation)