Grendon, meaning Green Hill (Don) or Green Valley (Dene) in Old English, may refer to:

Places Grendon, Northamptonshire, a small village in Northamptonshire, England Grendon, Atherstone, a civil parish in Warwickshire, England Grendon Underwood, a village and civil parish in Buckinghamshire, England HM Prison Grendon, a prison in Buckinghamshire, England New Grendon, a village in Warwickshire, England Old Grendon, a village in Warwickshire, England

People Stephen Grendon, a pen name of August Derleth

Fictional Dr. E. Grendon, the final character in Michael Cox's The Meaning of Night

Companies Thomas Grendon and Company, an Ironworks Foundry and Locomotive builder of Drogheda, Ireland

Titles Viscount Hatton, of Grendon