"American Gothic" is also the name of a storyline in comics related to the Swamp Thing.
American Gothic is a horror/western story from 2000 AD, created by Ian Edginton and Mike Collins.
Plot A group of freaks and monsters are trying to escape to a better life in the American West but are being hunted. A lone vampire cowboy eventually agrees to help them.
Publication American Gothic (by Ian Edginton and Mike Collins, in 2000 AD #1432–1440, 2005).
See also
Fiends of the Eastern Front, another major 2000 AD story containing vampires.
External links 2000 AD profile