PD2, Pd2 or PD-2 may refer to:
PD2, a model of the Leyland Titan double-decker bus PD2, a variant of the Plane Driven PD-1 roadable aircraft Pd2, Polish State Railways classification of Prussian S 4 steam locomotive Ukrspecsystems PD-2, a Ukrainian unmanned aerial vehicle PAF1, a human gene also called PD2
See also North American blizzard of 2003, also known as the Presidents' Day Storm II or "PDII" Payday 2, a cooperative first-person shooter video game The Princess Diaries 2: Royal Engagement, a 2004 American romantic comedy film