Patrick O'Reilly may refer to:
Patrick O'Reilly (Independent politician) (1893–1972), Irish independent politician represented Cavan, 1948–1951 Patrick O'Reilly (Longford politician) (1911–2003), Irish Fianna Fáil politician, member of the Senate, 1944–1969 Patrick O'Reilly (Cavan politician) (1906–1994), Irish Clann na Talmhan/Fine Gael politician represented Cavan, 1943–1973 Patrick O'Reilly (priest) (1843–1914), Catholic priest and educationalist Patrick J. O'Reilly (actor) (born 1980), Irish actor, director and writer Patrick J. O'Reilly (politician) (died 1965), Irish politician, member of the 5th Senate Patrick F. O'Reilly, Irish politician, member of the 7th Senate Patrick Thomas O'Reilly (1833–1892), Roman Catholic bishop of Springfield, Massachusetts Paddy O'Reilly (footballer) (1898–1974), soccer player Patrick W. O'Reilly (1925–2020), American lawyer and politician Patrick O'Reilly (ethnologist), French priest and ethnologist