William Chamberlain may refer to:
William Chamberlain (MP), (died 1445), British politician, MP for Truro and Southampton William Tankerville Chamberlain (1751–1802), Irish judge William Chamberlain (politician) (1755–1828), American Representative from Vermont William Charles Chamberlain (1818–1878), British Royal Navy rear admiral William H. Chamberlain (1931–1972), American politician William Chamberlain (technologist), author of the poetry-generating computer program Racter Bill Chamberlain (1949–2025), American basketball player Bill Chamberlain (baseball) (1909–1994), American Major League Baseball pitcher William Chamberlain (priest) (died 1666), English canon of Windsor William Joseph Chamberlain (died 1945), English journalist and pacifist
See also William Chamberlin (disambiguation) William Chamberlayne (disambiguation)