Doctor Octopus (Dr. Otto Octavius), also known as Doc Ock for short, is a fictional character appearing in American comic books published by Marvel Comics. The character was created by Stan Lee and Steve Ditko and first appeared in The Amazing Spider-Man #3 (July 1963). He is a highly intelligent, myopic, and stocky mad scientist who sports four strong and durable appendages resembling an octopus's tentacles, which extend from his body and can be used for various purposes. After his mechanical harness became permanently fused to his body during a laboratory accident, he turned to a life of crime, and came into conflict with the superhero Spider-Man. He has endured as one of Spider-Man's most prominent villains, and is regarded as one of his three archenemies, alongside the Green Goblin and Venom. He is the founder and leader of the Sinister Six, the first supervillain team to oppose Spider-Man.

While usually portrayed as a supervillain, Doctor Octopus has also been occasionally depicted as a conflicted antihero and ally of Spider-Man. Following Spider-Man's death in the 2012 storyline "Dying Wish", which saw a dying Octavius swapping bodies with the hero and letting him die in his original body, Octavius was motivated to prove he could be a better Spider-Man. As such, he adopted the Superior Spider-Man alias, introduced in Avenging Spider-Man #15.1 following a cameo in Daredevil vol. 3 #21 (both December 2012), as the third predominant main continuity Spider-Man. The Superior Spider-Man possesses all of the original Spider-Man's abilities, memories, and equipment, along with additional gadgets created by Octavius, though he often struggles to live up to his predecessor's legacy and seeks to turn his life around after being a villain for years.

In 2013, Marvel launched a 33-issue The Superior Spider-Man comic book series focusing on the character's redemption and superhero career, ending with the original Spider-Man being resurrected after the death of Otto Octavius. Following Spider-Verse, a copy of Octavius' consciousness became the anti-villain Superior Octopus, though a second volume of The Superior Spider-Man launched in 2018 saw the duplicate taking on the mantle and the new name Dr. Elliot Tolliver before returning to the Doctor Octopus mantle as an antihero, having his soul restored and memories of redemption erased by Mephisto, before returning to the role of Superior Spider-Man in 2023 in a new series by Dan Slott, and Spider-Man: Octo-Girl by Hideyuki Furuhashi and Betten Court, with his good and evil selves separated into different bodies. One of his evil selves, on being placed in a Wakandan body in 2026's Black Panther: Intergalactic, renames himself Otto Blacktavius / Golden Arms.

Comics journalist and historian Mike Conroy writes of the character: "Created by Stan Lee and artist Steve Ditko, Doc Ock, as he became known, has become one of the web-slinger's most persistent, enduring, and dangerous foes." A fan-favorite character and well-known figure in popular culture, Doctor Octopus has been featured in various media adaptations of Spider-Man over the years, including feature films, television series, and video games. In live-action, Alfred Molina portrayed the character in the films Spider-Man 2 (2004) and Spider-Man: No Way Home (2021). Kathryn Hahn voiced a female version of Doctor Octopus named Olivia "Liv" Octavius in the animated film Spider-Man: Into the Spider-Verse (2018), with the comic-book Lady Octopus then being redesigned after her, before, in 2025, Olivia Octavius was introduced to the main Earth-616 continuity in the "One World Under Doom" event as the future daughter of Otto Octavius.

Publication history Doctor Octopus first appeared in The Amazing Spider-Man #3 (July 1963), created by writer Stan Lee and artist Steve Ditko.DeFalco "1960s" in Gilbert (2008), p. 93: "Dr. Octopus shared many traits with Peter Parker. They were both shy, both interested in science, and both had trouble relating to women ... Otto Octavius even looked like a grown up Peter Parker. Lee and Ditko intended Otto to be the man Peter might have become if he had not been raised with a sense of responsibility.The Amazing Spider-Man #3 Lee recounted: "Usually in creating a villain the first thing I would think of was a name, and then I would try to think of, 'Well, now that I've got the name, who's the character going to be and what will he do?' For some reason, I thought of an octopus. I thought, 'I want to call somebody Octopus. And I want him to have a couple of extra arms just for fun'. But I had to figure out how to do that". The character reappeared in The Amazing Spider-Man #11–12, then again in #31–33.

Doctor Octopus is regarded as one of Spider-Man's most infamous enemies. He has been cited as the man Peter might have become if he had not been raised with a sense of responsibility. He is infamous for defeating Spider-Man the first time in battle and for almost marrying Peter's Aunt May. He is also the founder and core leader of the Sinister Six, and has referred himself as the "Master Planner". ("If This Be My Destiny...!") Later depictions revealed him in Peter Parker's body where he was the titular character from 2013 to 2014. In 2018, he returned as the Superior Spider-Man in a series written by Christos Gage and illustrated by Mike Hawthorne, and again in 2023 in a new series by Dan Slott, and Spider-Man: Octopus Girl by Hideyuki Furuhashi and Betten Court.

Fictional character biography Born in Schenectady, Otto Octavius was the only child of Torbert Octavius, a construction worker, and Mary Lavinia Octavius, a homemaker. While Mary loved and supported Otto right from the beginning, Torbert was a violent alcoholic who regularly beat Otto and his mother. The young Octavius's shyness and good work in school got him labeled as a "teacher's pet" and targeted as a subject for bullying. Torbert hated having a bullied son and, believing that a man's worth was determined by his dominant attitude and physical strength, roared at him to use violence in dealing with the bullies. Mary Octavius would always defend her son from Torbert's tirades, saying he was a gifted thinker who would use his brain to solve problems, not his fists. Due to his mother's insistence and her disgust towards men who worked in common manual labor, Octavius was determined not to become like his father and threw all his efforts into his education, regularly scoring top marks. Octavius' devotion to study paid off with him being awarded a university scholarship at M.I.T.. During Octavius's freshman year of college, he was undecided in his studies until they were briefly interrupted by Torbert's death in a construction accident. Otto attended the funeral for his mother's sake, although he himself did not mourn his father's death and later privately expressed his desire to have seen him suffer more. When Mary remarked that "an early death is a manual laborer's" and she expected better from her son, this seemed to spur an obsession in Octavius about the hard sciences, and he declared his major to be physical science. His obsession, however, did not manifest immediately, and he was regarded by his school friends as a devoted student who was genuinely interested in the studies. He graduated near the top of his class, and was considered a catch to many scientific firms. Octavius was soon hired by an engineering firm.Spider-Man/Doctor Octopus: Year One #1

Octavius became a respected nuclear physicist, atomic research consultant, inventor and lecturer. He designed a set of highly advanced mechanical arms controlled via a brain–computer interface to assist him with his research into atomic physics. The tentacle-like arms were resistant to radiation and were capable of great strength and highly precise movement, attached to a harness that fit around his body.

Criminal career begins During an accidental radiation leak that ended in an explosion, the apparatus became fused to Octavius' body. It was later revealed that the radiation, or possibly his own latent mutation, had mutated his brain so that he could control the movement of the arms using his thoughts alone. The tentacles have since been surgically removed from his body, although Octavius retains the power to control them telepathically from great distances. The accident also seemingly damaged his brain (although it was later suggested that what was interpreted as brain damage was, in fact, his mind rewiring itself to accommodate four extra limbs), and the scientist turned to a life of crime, first taking the hospital hostage and calling himself "Doctor Octopus" from the derogatory name that his co-workers had given him. Though Doctor Octopus himself is portly, in poor physical shape, and is near-sighted, with his harness attached he is physically more than a match for Spider-Man. The accident also made his eyes very sensitive to light, requiring him to wear glasses with shaded lenses.Spider-Man/Doctor Octopus: Negative Exposure #3

Over the years, Doctor Octopus has become one of the most identifiable members of Spider-Man's rogues gallery. Doctor Octopus formed the original Sinister Six to fight Spider-Man after taking Betty Brant and May Parker hostage.The Amazing Spider-Man Annual #1 He has led subsequent Sinister Six groups and usually takes offense when someone else leads the team. Disguised as the Master Planner, he organized theft of atomic equipment. After he stole a formula that Spider-Man needed to cure his Aunt May, Spider-Man tracked Doctor Octopus' gang to their base. In the ensuing fight, Spider-Man is trapped underneath a collapsed building. Seemingly doomed, Spider-Man overcomes.The Amazing Spider-Man #31-32 It is later revealed he used a scuba tank to escape.

Doctor Octopus later attempts to steal the Defense Department's Nullifier device, and sets a trap for Spider-Man.The Amazing Spider-Man #53 He became May Parker's tenant,The Amazing Spider-Man #54 then got close enough to use the Nullifier on Spider-Man; although he had hoped that it would merely nullify Spider-Man's web-shooters, the radiation in Spider-Man's blood resulted in the Nullifier's interaction with Spider-Man's unique biology rendering him amnesiac,The Amazing Spider-Man #55 Doctor Octopus subsequently tricking Spider-Man into helping him before Spider-Man's own better nature resulted in him turning against his 'partner' despite his memory loss long enough for John Jameson to use the Nullifier to shut down his tentacles.The Amazing Spider-Man #56

Doctor Octopus later exhibited the ability to activate his mechanical arms remotely, and used them to free himself from prison.The Amazing Spider-Man #88 His resulting battle with Spider-Man resulted in Captain George Stacy's death.The Amazing Spider-Man #89-90 Doctor Octopus later waged a gang war with Hammerhead.The Amazing Spider-Man #112-115 He attempted to wed May Parker to acquire an island with an atomic plant which she had recently (and unknowingly) inherited.The Amazing Spider-Man #130-131