Penygroes or Pen-y-groes may refer to any of several places in Wales:
Pen-y-groes, Gwynedd, a village in North Wales Penygroes railway station, a former station in the village Penygroes, Pembrokeshire Pen-y-groes, Carmarthenshire Pen-y-groes (electoral ward), an electoral division in Carmarthenshire Pen-y-groes, an electoral ward covering the village of Pen-y-groes, Gwynedd