Y101 may refer to one of the following radio stations:
KRRY, of Quincy, Illinois KWYE, of Fresno, California WHYA, of Cape Cod, Massachusetts WYOY, of Jackson, Mississippi CKBY-FM, of Smiths Falls and Ottawa, Ontario, identified as Y101 from 2004 to 2013 DYIO, of Cebu City, Philippines
Y101 may also refer to: Yttrium-101 (Y-101 or 101Y), an isotope of yttrium