Keightley () is an English surname.
Notable people named Keightley Archibald Keightley (1859–1930), member of the Theosophical Society. Bill Keightley (1926–2008), equipment manager for the University of Kentucky men's basketball team Charles Keightley (1901–1974), British general David Keightley (1932-2017), historian of early China Edwin W. Keightley (1843–1926), US politician Lisa Keightley (born 1971), Australian cricketer Thomas Keightley (historian) (1789–1872), historian Thomas Keightley (official) (1650–1719), official in Ireland Archibald Keightley Nicholson (1871–1937), stained glass maker
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