The Diocese of Tehuacán () is a Latin Church ecclesiastical territory or diocese of the Catholic Church in Mexico. It is a suffragan in the ecclesiastical province of the metropolitan Archdiocese of Puebla de los Angeles. The Diocese of Tehuacán was erected on 13 January 1962. Its cathedra is found within the Cathedral of the Immaculate Conception of Mary in the episcopal see of Tehuacán, Puebla.

Bishops Ordinaries Rafael Ayala y Ayala (1962 -1985) Norberto Rivera Carrera (1985 -1995), appointed Archbishop of México, Federal District; elevated to Cardinal in 1998 Mario Espinosa Contreras (1996 -2005), appointed Bishop of Mazatlán, Sinaloa Rodrigo Aguilar Martínez (2006 -2017), appointed Bishop of San Cristóbal de Las Casas, Chiapas Gonzalo Alonso Calzada Guerrero (2018 - )

Auxiliary bishop Lorenzo Cárdenas Aregullín (1978–1980), appointed Bishop of Papantla, Puebla

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