The Roman Catholic Diocese of San Andrés Tuxtla () (erected 23 May 1959) is a suffragan diocese of the Archdiocese of Jalapa. In 1962, it lost territory to form the Archdiocese of Jalapa and the Diocese of Veracruz. It also lost territory in 1984 with the formation of the Diocese of Coatzacoalcos.
Bishops Ordinaries Jesús Villareal y Fierro (1959-1965) Arturo Antonio Szymanski Ramírez (1965-1968), appointed Bishop of Tampico, Tamaulipas Guillermo Ranzahuer González (1969-2004) José Trinidad Zapata Ortiz (2004-2014), appointed Bishop of Papantla, Puebla Fidencio López Plaza (2015-2020), appointed Bishop of Querétaro, Querétaro. José Luis Canto Sosa (2021-present)
Coadjutor bishop Arturo Antonio Szymanski Ramírez (1960-1965)
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