Liu Wei Di Huang Wan, also known as Liuwei Dihuang teapills () or Six Flavor Rehmanni, is a prescription (方剂 fāng jì) in traditional Chinese medicine and pharmacy to treat yin deficiency. In Japanese kampo, it is known as "Rokumi-gan" (六味丸 ろくみがん, it is also known as Kampo #87). It is commonly made into Chinese patent medicine.
History The formula was created by Qian Yi as dihuang pill (地黄丸). It was published in "Xiao'er Yao Zheng Zhi Jue" (also known as "Key to Therapeutics of Children's Diseases" or "The Correct Execution of Pediatric Medicinals and Patterns" ) in 1119 by Qian Yi's student.
The formula was altered slightly when it was borrowed as a Japanese kampo formula. Some Chinese species of herbs were replaced with herbs found in Japan. For example, Alisma plantago-aquatica was replaced with Alisma orientale for zé xiè.
Derivatives
The Liuwei Dihuang Wan is one of the most important Chinese patent medicines, and is widely used in eastern Asia.Xinfeng Zhao, Yue Wang, Yuqing Sun. "Simultaneous determination of four bioactive constituents in Liuwei Dihuang Pills by micellar electrokinetic chromatography", Journal of Pharmaceutical and Biomedical Analysis, Volume 44, Issue 5, 3 September 2007, Pages 1183-1186. In China, there are hundreds of medicinal manufacturers who produce Liuwei Dihuang Wan and its derivatives. These derivatives include Zhibai Dihuang Wan, Guifu Dihuang Wan, Mingmu Dihuang Wan, Qiju Dihuang Wan, Maiwei Dihuang Wan, and Guishao Dihuang Wan.
Chinese classic herbal formula
NameCommon NamePinyinChinese (T)Chinese (S)KatakanaKanjiGenus speciesAction in this formulaRehmanniae RadixChinese foxglove rootshú dì huáng熟地黃熟地黄ジオウ地黄Rehmannia glutinosaNourishes kidney yin & essenceCorni FructusHuahong Wang, Zhezhi Wang, Wubao Guo. "Comparative determination of ursolic acid and oleanolic acid of Macrocarpium officinalis (Sieb. et Zucc.) Nakai by RP-HPLC", Industrial Crops and Products, Volume 28, Issue 3, November 2008, Pages 328-332.Japanese cornel fruitshān zhū yú山茱萸山茱萸サンシュユ山茱萸Cornus officinalisNourishes the liver & kidney, restrains the leakage of the essenceDioscoreae RhizomaChinese yam rhizomeshān yào山藥山药サンヤク山薬Dioscorea polystachyaTonifies spleen yin & consolidate the essenceAlismatis Rhizomawater plantain rhizomezé xiè澤瀉泽泻タクシャ沢瀉Alisma plantago-aquaticaPromotes urination to prevent buildup of significant fluidsPoriatuckahoe mushroomfú líng茯苓茯苓ブクリョウ茯苓Poria cocosBland: drains dampness from the spleenCortex Moutan Radicis Cortextree peony barkmǔ dān pí牡丹皮牡丹皮ボタンピ牡丹皮Cortex Moutan RadicisClear liver fire
Japanese kampo formula
NameCommon namePinyinChinese (T)Chinese (S)KatakanaKanjiGenus speciesGrams%Rehmanniae RadixChinese foxglove rootshú dì huáng熟地黃熟地黄ジオウ地黄Rehmannia glutinosa5.025%Corni FructusJapanese cornel fruitshān zhū yú山茱萸山茱萸サンシュユ山茱萸Cornus officinalis3.015%Dioscoreae RhizomaJapanese yam rhizomeshān yào山藥山药サンヤク山薬Dioscorea japonica3.015%Alismatis Rhizomawater plantain rhizomezé xiè澤瀉泽泻タクシャ沢瀉Alisma orientale3.015%Poriatuckahoe mushroomfú líng茯苓茯苓ブクリョウ茯苓Poria cocos3.015%Paeoniae suffruticosa Cortextree peony barkmǔ dān pí牡丹皮牡丹皮ボタンピ牡丹皮Paeonia suffruticosa3.015%
See also Chinese herbology Chinese patent medicine Chinese classic herbal formula Kampo list Kampo herb list Zhibai Dihuang Wan
References