NPE may refer to:
Transport Napier Airport, New Zealand, by IATA code New Pantai Expressway, an expressway in Klang Valley region, Malaysia Nationale Plattform Elektromobilität, the German National Platform for Electric Mobility
Science and technology New political economy, a sub-school within the field of political economy Nonylphenol ethoxylates, mixtures of nonionic surfactants Non-paternity event, a paternal relationship that is shown to be false through DNA testing Norton Power Eraser, a tool that scans a computer system for threats Null pointer exception, a form of run-time error in many programming languages
Other National Party of Europe, in politics National Policy on Education, in India New Popular Edition, maps published by the Ordnance Survey Non-practicing entity, a type of patent owner