Plavšić or Plavsic is a Serbian surname. Notable people with the surname include:
Biljana Plavšić (1930–2026), Bosnian Serb politician Adrien Plavsic (born 1970), Canadian hockey player Branko Plavšić (1949–2011), Serbian comic book artist Nikolina Plavšić (born 2001), Serbian footballer Srđan Plavšić (born 1996), Serbian football player