Tusculum is a ruined Roman city in the Latium region of Italy.
Tusculum may also refer to:
Places Tusculum, Potts Point, a heritage-listed house in Potts Point, Sydney, Australia
United States Tusculum (Princeton, New Jersey), a 1773 country estate, listed on the National Register of Historic Places Tusculum (Arcola, North Carolina), an 1835 plantation house, listed on the National Register of Historic Places Tusculum (Amherst, Virginia), a c. 1805 house, listed on the National Register of Historic Places Tusculum, Tennessee, a city Tusculum College, a university in Tennessee Tusculum, Nashville, Tennessee, a neighborhood
Other uses Counts of Tusculum, secular noblemen in Latium during the tenth through twelfth centuries Battle of Tusculum, an 1167 battle between the Holy Roman Empire and the Commune of Rome
See also Columbia-Tusculum, Cincinnati, Ohio, a neighborhood