Eastern Macedonia most commonly refers to the western part of Eastern Macedonia and Thrace, in Greece.

It may also refer to:

eastern parts of the wider geographical and historical region of Macedonia Pirin Macedonia, the part of the region of Macedonia in Bulgaria Eastern Statistical Region, a statistical region in modern North Macedonia eastern parts of the ancient Kingdom of Macedonia eastern parts of the ancient Roman Province of Macedonia Eastern Macedonia Army Section, an army group of the Hellenic Army in World War II Technological Educational Institute of Eastern Macedonia and Thrace, an institute in Kavala, Greece

See also Macedonia (theme) Macedonia (disambiguation) Western Macedonia (disambiguation)