Thigpen is a family name that may refer to:
Ben Thigpen (1908–1971), American jazz drummer Corbett H. Thigpen (1919–1999), American psychiatrist Cressie Thigpen (born 1946), American jurist and lawyer Ed Thigpen (1930–2010), American jazz drummer Ivory Torrey Thigpen Jr., American politician Lynne Thigpen (1948–2003), American actress Owen Thigpen/Fitzpen/Phippen (1582–1636), English merchant Richard Ashley Thigpen (born 1943), American academic Anita Thigpen Perry (born 1952), First Lady of Texas
Athletes Bobby Thigpen (born 1963), American baseball player Curtis Thigpen (born 1983), American baseball player J. H. Thigpen, American college football player Justus Thigpen (born 1947), American basketball player Marcus Thigpen (born 1986), American football player Tommy Thigpen (born 1971), American college football player and coach Tyler Thigpen, (born 1984) American football player Yancey Thigpen (born 1969), American football player