DMX (born Earl Simmons; 1970–2021) was an American rapper.

DMX may also refer to:

People DMX Krew (born Ed Upton), British electronic music artist Davy DMX (born David Reeves; born 1960), American hip hop music pioneer

Science 5-Dehydro-m-xylylene, the first organic molecule known to violate Hund's rule Depressive mixed state, a psychological disorder DmX gene, an extremely large WD-protein coding gene found in eukaryotes

Technology DMX512, a communications protocol that is most commonly used to control stage lighting and effects Symmetrix DMX, a series of enterprise storage arrays by EMC Corporation Data Mining Extensions, a query language for data mining models DMX, a protocol for fracture modeling in geoscience

Other uses DMX (music service), a retail environment company Oberheim DMX, a drum machine manufactured by Oberheim National Weather Service Des Moines, Iowa, whose office identification code is DMX

See also Dextromethorphan (DXM)