Patrick Byrne may refer to:

Sports Patrick Byrne (sledge hockey) (born 1965), American ice sledge hockey player Patrick B. Byrne (born 1956), American horse trainer Paddy Byrne, Irish Free State football player in the 1930s Pat Byrne (footballer) (born 1956), Irish football player and manager

Music Patrick Byrne (musician) (1794–1863), Irish traditional musician Pat Byrne (singer) (born 1991), winner of the first series of The Voice of Ireland

Others John Byrne (playwright) (born 1940), who, as a painter, uses the name Patrick Byrne Patrick Anthony Langan-Byrne (1895–1916), Irish British flying ace Patrick Byrne (architect) (1783–1864), Irish architect Patrick Byrne (Irish politician) (1925–2021) Patrick James Byrne (1888–1950), American Catholic missionary and bishop in Korea and Japan Patrick M. Byrne (born 1962), American entrepreneur, founder and former CEO of Overstock.com Patrick Michael Byrne (anthropologist) (1856–1932), Paddy and Pado, scientist and telegraph master at Charlotte Waters Patrick Byrne (fl. 1795–1837), of Clone, Ireland, in the list of monumental masons Patrick Byrne (commissioner) (born 1946), Irish Police Commissioner.

See also Pat Byrnes, cartoonist Patrick Burns (disambiguation)