Itoi () may refer to:

People Shigesato Itoi, Japanese author and game designer Yoshio Itoi, Japanese professional baseball player Hajime Itoi, Japanese backstroke swimmer

Places Itoi Station, a railway station on the Muroran Main Line in Tomakomai, Hokkaidō, Japan Izushi-Itoi Prefectural Natural Park, is a Prefectural Natural Park in northeast Hyōgo Prefecture, Japan Itoi (Hitui), a village in India

See also I'itoi, the cosmology of the O'odham peoples