Henry Willoughby may refer to:
Sir Henry Willoughby (courtier) (1451–1528), English courtier Henry Willobie (c. 1575–c. 1596), or Willoughby, English author Sir Henry Willoughby, 1st Baronet (1579–1649), see Willoughby baronets Henry Willoughby, 4th Baron Willoughby of Parham (1612–1617), English peer Henry Willoughby (colonial administrator) (1640–1669), British governor of Antigua and Barbados Henry Willoughby, 16th Baron Willoughby of Parham (1696–1775), English peer Henry Willoughby, 5th Baron Middleton (1726–1800), English peer Henry Willoughby, 6th Baron Middleton (1761–1835), English peer, son of the above Henry Willoughby (Newark MP) (1780–1849), member of Parliament for Newark Sir Henry Willoughby, 3rd Baronet (1796–1865), British politician Henry Willoughby, 8th Baron Middleton (1817–1877), English peer