Semtex is a general-purpose plastic explosive.

Semtex may also refer to: Semtex (album), a 1996 album by The Third Eye Foundation Semtex (drink), a taurine-containing energy drink manufactured in the Czech Republic DJ Semtex, a BBC hip-hop disc jockey and producer from the UK Paul "Semtex" Daley (b. 1983), a British mixed martial artist Semtex (anti-slip covering), a type of gritty cement-like compound used on the decks of Royal Navy ships