NRDC may refer to:

Natural Resources Defense Council, an American environmental group National Research Development Corporation, a UK company set up to license government research to industrial partners NRDC Equity Partners, an American retail holding company NATO Rapid Deployable Corps – Italy, an Italian military formation. U.S. Army Natick Research and Development Center, a research and development center for soldier equipment Nardilysin, an enzyme encoded by the gene NRDC

See also National Research Development Corporation v Commissioner of Patents, a 1959 Australian patent law case NDRC (disambiguation)