Life's a Bitch may refer to:

Albums Life's a Bitch (album), a 1987 album by Raven

Songs "Life's a Bitch" (song), a 1994 song by Nas from his album Illmatic "Life's a Bitch", a 1999 song by Shooter from the Songs from Dawson's Creek soundtrack "Life's a Bitch", a 2004 song by Motörhead

Films Life's a Bitch (2013 film), a Canadian short film Life's a Bitch (2023 film), a Belgian black comedy film

See also Life Is a Bi..., a 2021 EP by singer Bibi Isn't Life a Bitch?, a 1931 French film by director Jean Renoir