was a samurai and daimyō (feudal military lord) during the Sengoku period and Azuchi–Momoyama period. He was the third son of Mōri Motonari who was adopted by the Kobayakawa clan and became its 14th clan head. He merged the two branches of the Kobayakawa, the Takehara-Kobayakawa clan (竹原小早川氏) and Numata-Kobayakawa clan (沼田小早川氏). He became an active commander of the Mōri army and he with his brother Kikkawa Motoharu became known as the “Mōri Ryōsen", or “Mōri's Two Rivers" (毛利両川). As head of the Kobayakawa clan, he expanded the clan's territory in the Chūgoku region (western Honshū), and fought for the Mōri clan in all their campaigns

At first he opposed Oda Nobunaga and Toyotomi Hideyoshi but later swore loyalty and became a retainer of Hideyoshi who awarded him domains in Iyo Province on Shikoku and Chikuzen Province on Kyūshū, totalling 350,000 koku. Hideyoshi gave him the title Chûnagon also appointed him to the Council of Five Elders but died before Hideyoshi himself.

Biography Early life He was born in 1533 with the childhood name Tokujumaru (徳寿丸) as the third son of Mōri Motonari and his main wife Myōkyū. In 1541 the 13th head of the Takehara branch of the Kobayakawa clan, Kobayakawa Okikage (小早川興景), got ill and died while attacking Sato-Kanayama Castle (佐東銀山城). In November, 1543 since he had no heir Tokujumaru was declared successor because he was a cousin of Okikage's wife. So at twelve years of age he had become the 14th head of the Takehara-Kobayakawa clan (竹原小早川氏) and received the name Kobayakawa Takakage (小早川隆景).

In 1547, when Ōuchi Yoshitaka attacked Kannabe castle (神辺城) in Bingo Province, Takakage served as one of his commanders and was highly commended for capturing Kannabe castle's support castle (支城), the Ryuoyama Fort (龍王山砦) with the Kobayakawa army alone.

The other branch of the Kobayakawa clan was the Numata-Kobayakawa clan (沼田小早川氏). The head of the family, Kobayakawa Shigehira (小早川繁平) was young and blind due to an eye disease so in 1550 it was decided that Takakage would become heir of the Numata branch and finally merge the two rival branches of the clan. The Takehara-Kobayakawa branch ceased to exist and Takakage moved into Takayama Castle (高山城), the main base of the Numata branch. In 1552 Takakage decided to build a new main castle across the Numata River (沼田川) and called it is Niitakayama Castle (新高山城). He married Lady Toida, daughter of Kobayakawa Masahira and sister of the blind Kobayakawa Shigehira in order to cement his succession. They would never have children for unknown reasons but they would later adopt to keep the clan alive.

After this the Kobayakawa clan was incorporated into the clans following the powerful Mōri clan of his father, Mōri Motonari. The Kobayakawa would become an important naval force under the direct control of his father. His older brother, the second son of Motonari was adopted into the Kikkawa clan and became Kikkawa Motoharu. They were both together pillars of the Mōri forces and were known as "Mōri's Two Rivers" (Mōri Ryōsen, 毛利両川).

In 1555 at the Battle of Miyajima, Takakage led his naval forces under control of the Mōri clan and broke the naval blockade of the Ōuchi clan forces under the command of Sue Harukata. He sailed straight toward Miyao Castle in a feint, then retreated so he could be in a position to return the following day, his attack synchronized with the overland assault. At dawn, Takakage and his 1,500 troops landed before the small fortress, and the sound of shell trumpets signalled that all units were in position and the attack commenced. As Takakage's force rushed the front gate of Miyao Castle, Mōri and his troops hit the Ōuchi position from behind. Caught completely by surprise, many of the Ōuchi troops scattered in disarray. Hundreds tried to swim to the mainland and drowned in the attempt. Many more saw that defeat was inevitable and committed seppuku (honorable suicide). By 18 October 1555, resistance had ended at a cost of about 4,700 dead among the Ōuchi army. Sue Harukata escaped from the confines of Miyao Castle, but when he saw that escape from the island was not possible, he also committed suicide by seppuku.

In 1557 Takakage took part of the Conquest of Bōcho (防長経略) and the Mōri forces took both Suō Province and Nagato Province of the Ōuchi clan and Ōuchi Yoshinaga committed suicide. They took Yoshinaga's Moji Castle in 1558 but in September, 1559 it was retaken by Ōtomo Yoshishige. Then in 1561 Kobayakawa again led the Mōri navy in the recapture of the castle in the Siege of Moji. During the same year his father, Mōri Motonari retired in favor of his first son and heir apparent (Takakage's eldest brother), Mōri Takamoto. Under Takamoto, Takakage continued to be a main force of the Mōri along with his second older brother Kikkawa Motoharu. In 1561

In 1563 Mōri Takamoto suddenly died of illness and his son (Takakage's nephew) Mōri Terumoto became head of the Mōri clan. While the 2nd brother Kikkawa Motoharu was in charge of military affairs, Takakage took responsibility of political affairs. He worked on diplomacy, taking advantage of the information gathering capabilities of the military. In the Siege of Toda Castle (1562–1566) they destroyed their enemy, the Amako clan (尼子氏). During the following year of 1567 he was dispatched to help the Kôno clan (河野氏) of Iyo Province and at the Battle of Torisaka captured Ozu Castle (大洲城) forcing Utsunomiya Toyotsuna (宇都宮豊綱) to surrender. Takakage was then also dispatched to fight the Ōtomo clan (大友氏) in Kyūshū. When Murakami Michiyasu (村上通康) died that year Takakage sent his widow who was a daughter of Kôno Michinao to marry Shishido Takaie.

In 1568 Kobayakawa Takakage fought in the Battle of Torisaka and the 1568 Battle of Tatarahama. In 1570 he fought in the Battle of Nunobeyama. In 1571, Takakage was sent to help the Mimura clan (三村氏) of Kojima (児島), Bizen Province against Urakami Munekage (浦上宗景) but the Murakami and Awa Pirates helped and Takakage was forced to withdraw to Aki Province.

After the death of Mōri Motonari in 1571, "Mōri's Two Rivers" (Kobayakawa Takakage and Kikkawa Motoharu) became more important as assistants to Mōri Terumoto against the remnants of their enemies, the Ōtomo clan (大友氏), Amako clan (尼子氏), and Ōuchi clan (大内氏).

Conflict against Ōtomo clan

In 1556 at May 19, Dōsetsu's forces finally manage to quell the rebellions incited by Akimoto, and he later sent recommendation letters of his subordinates who gave outstanding performance during this operation, such as Korenobu Yufu, Takano Daizen, Adachi Sakyō, and Ando Iesada.

In 1557, the Akizuki clan rebelled due to their collaboration with Mōri Motonari, to which Sorin responded by sending Tachibana Dōsetsu and Usuki Akisumi with 2,000 soldiers to quell their rebellion. Dōsetsu besieged the Akizuki clan which was led by Akizuki Kiyotane in . In the end, Kiyotane and his son committed seppuku inside their castle.

In the next year of 1558, Dōsetsu fought Mōri clan sent Takakage in the first siege of Moji castle. In this battle, Dōsetsu had 800 of his archers shower Kobayakama's army with arrows. As the Dōsetsu continues his siege until 1562, Dōsetsu entered the last phase of this Siege of Moji, where he enlisted the help of traders from Portuguese Empire In this battle, the Portuguese merchants assisted Dōsetsu with three ships weighted between 500-600 tons, The bombardment from the ships allowed the Ōtomo troops to establish themselves around Moji castle. However, the castle defenders manage to break the siege after the Portuguese has spent all their ammunitions and withdrew from this operation. Despite the Ōtomo forces under Dōsetsu launching another attempt at besieging the castle in 10 October 1561, they failed to subdue the castle.

In 1562 of July 13, Dōsetsu and his subordinate Korenobu Yufu, has defeated the Mōri clan army in the battle in Yanagigaura in Buzen Province.刀 無銘 兼光 Later, Dōsetsu stormed Moji castle on October 13 and they managed to subdue the castle which was defended by Reizei Mototoyo, a former Ouchi clan vassal who was 25 years old. On November 26, there was a battle all day long near Moji Castle, leaving hundreds injured and dead with an unclear result. In 1563, on the New Year's Day of 6th year of Eiroku, a large army led by Mōri Takamoto and Kobayakawa Takakage arrived to relieve Moji castle. The army of Dōsetsu and Mōri Takamoto entered a standoff until an intermediary envoy from Kyoto arrived sending a message from the Ashikaga shogunate to both Dōsetsu and Takamoto to stop their conflict. In the same year, Dōsetsu changed his name from Akitsura into Dōsetsu.『豊津町史』第四編 中世(鎌倉・室町・安土桃山時代) 第四章 戦国時代の豊前国 二 大友氏と毛利氏の衝突 松山城の攻防(『浦文書』・『萩藩閥閲録』) 『井樓纂聞 梅岳公遺事』 p.26~27戸次鑑連剃髪之事 In 1564 July 25, the mediator from the Shogunate secured an agreement of temporary peace treaty between the Mōri clan and the Ōtomo clan. However, this truce did not last long as on March 25, Dōsetsu once again fought the Mōri clan army which was led by Koremaki Yufu in The Fourth Battle of Yanagigaura.

In 1569, Dōsetsu was involved in the failed defense of the Siege of Tachibana castle, where the army under Mōri Motonari beat Dosetsu forces with the extensive use of cannons. Later in the same year, Dōsetsu personally led the Otomo forces against the Mōri clan in Tatara area (located in modern day Higashi-ku, Fukuoka), where they engaged in at least four battles which ended in deadlocks.

In May 18, after several engagements at the Battle of Tatarahama, the Ōtomo army led by Dōsetsu, Usuki Akisumi, and Yoshihiro Akimasa clashed against 40,000 soldiers under Kikkawa Motoharu and Kobayakawa Takakage.『福岡県史資料. 第4輯』立花文書 『柳河戦死者名譽錄』(一二)筑前多々良濱 永禄十二年五月十八日 P.8~9多々良川の戦い 戸次鑑連の奮戦 『柳川市史』史料編V近世文書(前編)61 立花文書 三二 大友宗麟軍忠一見状 永禄十二年五月十八日、立花表於敵陣、長尾岸渥防戦之砌、戸次伯耆守鑑連親類・与力・被官、或分捕高名被疵、或戦死之着到、銘々加披見訖、 P.346~348。 During the fierce battle between the two sides, Dōsetsu lead the charge into the enemy formation and killed more than ten enemies and manage to beat the vanguard of Motoharu which was led by Yoshikawa Motoharu's vanguard led by Nobuki Narazaki. Then, Yoshikawa Motoharu used iron cannons to counterattack. The situation was described as dire for the Ōtomo side before Dōsetsu charged towards a gap in the formation of Takakage's army, allowing other Dōsetsu generals to reorganize themselves and rearrange their artillery. Dōsetsu rode his horse and charged forward unto the enemy camp while drawing his sword.The army of Motoharu and Takakage was unable to resist and was pushed back.

Following the battle of Tatatahama, there are about 18 more clashes in the area from 21–26 May, between Dōsetsu army against Takakage and other Mōri generals with undetermined results. However, in the end Takakage forced to relinquish the castle of Tachibana again to Dōsetsu, since the Mōri and Ōtomo clan sign truce peace negotiation with the result that Mōri clan should give back the Tachibana castle to Ōtomo.

Conflict with Nobunaga

The 15th shōgun of the Ashikaga shogunate, Ashikaga Yoshiaki had a falling out with Oda Nobunaga in 1576 and invited Mōri Terumoto to join the 3rd Nobunaga Encirclement Plan (第3次信長包囲網). The alliance consisted of Ashikaga Yoshiaki, Mōri Terumoto, Uesugi Kenshin, Takeda Katsuyori and the Ishiyama Hongan-ji monks. The allies really didn't have too much success against the powerful Oda armies. The significant event here is the formation of all these powerful men, who were oftentimes not the best of friends. That same year (1576) at the First Battle of Kizugawaguchi, Kobayakawa Takakage led the Mōri naval forces with Murakami Takeyoshi. The Mōri navy successfully thwarted an Oda blockade of the Ishiyama Honganji led by Kuki Yoshitaka.