OFC may refer to:

Business and financial Corporate Office Properties Trust, its NYSE ticker symbol Offshore financial centre, a term synonymous with a tax haven Conduit and sink OFCs, a categorisation of offshore financial centres/tax havens Optional federal charter, a proposal to streamline and simplify US insurance regulation Ottawa Folklore Centre, a former instrument and music store in Ottawa, Canada

Media and entertainment Online Film Critics Society Open-face Chinese poker, a Chinese poker variant Order from Chaos, a band

Sport Oceania Football Confederation Kickers Offenbach, a German association football club Odisha FC, an Indian professional football club OFC Oostzaan, a Dutch association football club Orpington F.C., an English non-league football club

Science and technology Osteitis fibrosa cystica, a skeletal disease involving the parathyroid glands Open fiber control, a telecommunication protocol Optical fiber, conductive, a type of optical fiber cable Orbitofrontal cortex, a region of the brain involved in decision making and other cognitive functions Oxygen-free copper, a copper cable manufacturing process Oxy-fuel cutting, a metal cutting process; See Oxy-fuel welding and cutting Open Financial Connectivity, a financial transition file format Occipitofrontal circumference, a way to measure the fetal head

Other uses ofc, an SMS language abbreviation for "of course" Officer railway station, Melbourne Schenley OFC Whisky, a whisky brand Daihatsu OFC-1, car brand