Isozaki () is a Japanese surname. Notable people with the surname include:
Arata Isozaki, Japanese architect Chitoshi Isozaki (1913–1993), Japanese fighter pilot Hiromi Isozaki (athlete) (born 1965), Japanese sprint athlete Hiromi Isozaki (born 1975), maiden name of Japanese footballer Hiromi Ikeda Keita Isozaki (born 1980), Japanese footballer Naomi Isozaki, Japanese Paralympic archer Yosuke Isozaki (born 1957), Japanese politician
See also Isozaki Station, train station in Japan Isozaki Atea, building in Spain