I0 or I-0 (the letter "I" followed by the digit "0", zero) may refer to:
Axiom I0, a rank-into-rank axiom in set theory I-0 (video game), a piece of interactive fiction written by Adam Cadre
See also IO (disambiguation) (the letter "I" followed by the letter "O") 10 (disambiguation) (the digit "1" followed by the digit "0") 1O (disambiguation) (the digit "1" followed by the letter "O") 0I (disambiguation) (the digit "0" followed by the letter "I")