Sienra can refer to:
A beach town in Asturias, Spain: San Pelayo de Sienra A large family that originated in Spain that emigrated to other areas of the world, especially Uruguay. Some notable members of this family include:
Gisel Silva Sienra, semi-finalist in Miss World 1988 representing Uruguay José Luis Zorrilla de San Martín, Uruguayan sculptor Luis Casaravilla Sienra, well-known tango musician, friend of Carlos Gardel Myriam Sienra (1939–2020), Paraguayan actress Rodolfo Sienra, President of the Club Nacional de Futbol soccer team, 1983–1985. Vera Sienra, Uruguayan singer