TPO may refer to:
Arts Taipei Philharmonic Orchestra Thailand Philharmonic Orchestra Tin Pot Operation, an indie-punk band from Belfast, Northern Ireland Tokyo Philharmonic Orchestra Turku Philharmonic Orchestra, Finland
Biology and medicine the temporo-parieto-occipital junction of the brain Thyroid peroxidase (or thyroperoxidase), an enzyme in the thyroid Thrombopoietin, a hormone stimulating platelet growth
Government Transportation Planning Organization, United States
Law Temporary protective order, a court order banning someone from going near a third party that they have allegedly harassed, in Ireland or the United States a tree preservation order in the United Kingdom
Science and technology Thermoplastic olefin, a plastic polymer/filler blend Transmitter power output in radio transmission Trimethylbenzoyl diphenylphosphine oxide, a photoinitiator used in UV-curable systems, such as artificial nail products, to enable rapid hardening under UV light
Other The People's Operator, a mobile virtual network operator in the United Kingdom Third-party ownership in association football A transit patrol officer of Victoria Transit Patrol, Australia Travelling Post Offices, mail trains in Great Britain and Ireland Travelling Post Office, Queensland, mail trains in Australia Treatment plant operator, an operator of water and waste water treatment plants Triple peel on opponent manoeuvre in croquet