Route 275 or Highway 275 may refer to:
United Kingdom
M275 motorway
Canada Manitoba Provincial Road 275 New Brunswick Route 275 Quebec Route 275
India National Highway 275 (India) State Highway 275 (Maharashtra)
Japan Japan National Route 275
United States Interstate 275 (multiple highways) U.S. Route 275 Alabama State Route 275 California State Route 275 Connecticut Route 275 Florida State Road 275 (former) Georgia State Route 275 Maryland Route 275 Minnesota State Highway 275 Montana Secondary Highway 275 New Mexico State Road 275 New York State Route 275 Tennessee State Route 275 Texas State Highway 275 Texas State Highway Loop 275 Farm to Market Road 275 (Texas) Utah State Route 275