GLC may refer to:
Music GLC (rapper) (born 1975), American rapper signed to Kanye West's G.O.O.D. Music record label Goldie Lookin Chain, Welsh rappers
Technology Gas-liquid chromatography Geographic Locator Codes Global Linear Collider, now merged into the International Linear Collider proposal Great Lakes Central Railroad Mazda GLC, a compact car Mercedes-Benz GLC, an SUV
Television "GLC: The Carnage Continues...", an episode of the television series The Comic Strip Presents... God's Learning Channel, an American television station Guyana Learning Channel, a Guyanese television channel Good Luck Charlie, Disney Channel sitcom
Other uses Gazankulu Liberation Congress, a minor South African political party Glasgow Central railway station, in Scotland Glucose Government-linked company Government Law Center, a research institute at Albany Law School, Albany, New York, United States Government Law College (disambiguation) Greater London Council, top-tier local government administrative body for Greater London from 1965 to 1986 Great Lakes Commission Green Lake Crew, a rowing club based in Seattle, Washington, United States Gutnius Lutheran Church, in Papua New Guinea Government-linked companies, a term used for state-owned enterprises of Malaysia